Column chromatography silica gel appears to be white powder. It dissolves in HF and strong caustic solution and can adsorb moisture in the air. Due to the duration time difference of absorption to different substances, it can separate and purify different substances.
This product is mainly used in refining of oil products for removing aromatic hydrocarbon substance or selective adsorption and separation of organic gases and liquids; and used as catalyst carrier and chromosorb; it can also be used for the separation and purification of effective compositions of Chinese herbal medicine as well as preparation of highly pure substances.
Column chromatographic silica gel plays an important role in the fields of chemistry, biology, medicine, etc., especially in the separation and purification of active ingredients of Chinese herbal medicine and the preparation of high-purity substances. For example, the heart-protecting drug coenzyme Q10, the anti-cancer drug paclitaxel, the organ transplant anti-rejection drug cyclosporin, etc., all use column chromatography to purify active ingredients.
The surface composition, specific surface size, pore capacity, pore size and pore size distribution of silica gel have a great impact on its adsorption capacity. Therefore, products with different pore structures can be prepared by controlling the process route or process conditions to meet the needs of different application fields.